• 1P-LSD vs Psilocybin: What’s the Difference?

    If you’re exploring microdosing, you’ve likely come across both psilocybin and 1P-LSD. These two compounds are among the most widely used psychedelics for enhancing focus, mood, and creativity—especially in low, sub-perceptual doses.

    While both have similar benefits, they differ in chemistry, effects, duration, and legality. This article breaks it down so you can make an informed choice for your personal wellness stack.

    What Is Psilocybin?

    Psilocybin is the active compound found in psychedelic mushrooms. Once ingested, your body converts it into psilocin, which interacts with serotonin receptors to alter perception and mood.

    It’s the more “natural” option of the two, and many users describe its effects as emotionally grounding, heart-opening, and ideal for enhancing emotional well-being.

    🍄 Try it: Psilocybin Microdose Capsules (100mg) – ideal for beginners and mood support.

    What Is 1P-LSD?

    1P-LSD (short for 1-propionyl-lysergic acid diethylamide) is a semi-synthetic analogue of LSD-25. It’s believed to act as a prodrug, meaning your body converts it into LSD once ingested.

    1P-LSD is popular for its precision, clarity, and energy. Users often report it’s better for cognitive performance, deep work, and problem solving—making it a favorite among entrepreneurs, coders, and creatives.

    ⚡ Explore: 1P-LSD Blotters (10mcg) – perfect for structured microdosing and clean mental energy.

    Key Differences at a Glance

    FeaturePsilocybin1P-LSD
    SourceNaturally occurring in mushroomsLab-synthesized analogue of LSD
    Onset30–60 minutes45–90 minutes
    Duration4–6 hours8–12 hours
    FeelEarthy, emotional, introspectiveAnalytical, energizing, focused
    Best ForMood, creativity, connectionFocus, productivity, structure
    Legality in CanadaControlled substanceLegal grey area

    Which One Is Right for You?

    It depends on your goals.

    • Choose psilocybin if you’re seeking emotional balance, mood support, or a deeper sense of presence.
    • Choose 1P-LSD if you want cognitive clarity, longer-lasting effects, and enhanced productivity.

    You can also alternate between both to support different types of work or wellness phases.

    What About Legality?

    • Psilocybin is a Schedule III controlled substance in Canada. While decriminalization efforts are growing, it remains technically illegal to possess or distribute without special exemption.
    • 1P-LSD, however, is not explicitly scheduled in Canada, making it accessible through platforms like Neurodose. This legal grey area makes it a popular choice for those seeking a compliant way to explore microdosing.

    🧠 Also consider: Adaptogen Blend Capsules – combining psilocybin, lion’s mane, and calming herbs for whole-body support.

    Final Thoughts: Try Both, Safely

    There’s no one-size-fits-all approach to microdosing. Whether you gravitate toward the natural feel of psilocybin or the clean focus of 1P-LSD, both compounds offer unique pathways to enhanced well-being.

    Neurodose offers safe, beginner-friendly options for both substances, all lab-tested and carefully dosed.

    Neurodose